A computer game that induces mice to experience hallucination-like events could be a key to understanding the neurobiological roots of psychosis, according to a study from Washington University School of Medicine in St. Louis.
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MADISON - Bipolar disorder affects millions of Americans, causing dramatic swings in mood and, in some people, additional effects such as memory problems.
While bipolar disorder is linked to many genes, each one making small contributions to the disease, scientists don t know just how those genes ultimately give rise to the disorder s effects.
However, in new research, scientists at the University of Wisconsin-Madison have found for the first time that disruptions to a particular protein called Akt can lead to the brain changes characteristic of bipolar disorder. The results offer a foundation for research into treating the often-overlooked cognitive impairments of bipolar disorder, such as memory loss, and add to a growing understanding of how the biochemistry of the brain affects health and disease.
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Cultural lives of animals revealed
The idea that only humans have culture and that this neatly separates us from animals is challenged by an extensive review of decades of research into animal culture by a leading expert in animal behaviour at the University of St Andrews.
Professor Andrew Whiten, Emeritus Wardlaw Professor of Evolutionary and Developmental Psychology in the School of Psychology and Neuroscience at the University of St Andrews, argues the case in a wide-ranging review published in the journal Science surveying all that has been discovered in recent decades about how animals create their own cultures.
Researchers reveal novel therapeutic target in the treatment of certain cancers
Mount Sinai Researchers Find Removal of AKAP11 Protein by Autophagy as a key to Fuel Mitochondrial Metabolism and Tumor Cell Growth through activating protein kinase A (PKA) (Patent pending)
Corresponding Author: Zhenyu Yue, PhD, Professor of Neurology, Aidekman Family Professorship, Director of Basic and Translational Research in Movement Disorders, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai.
Bottom Line: We uncovered a mechanism that tumor cells exploit selective autophagy for metabolic reprogramming that benefits tumor cell growth and offers resistance to glucose deprivation. Our study suggests that AKAP220-mediated autophagy as a novel therapeutic target for specific cancer treatment.
People with hearing impairments have been substantially affected by the impact of social isolation
Cancellation of medical appointments, the use of face masks and the limitation in the use of technology due to hearing loss are thought to all be important factors
Around 70 per cent of people over the age of 70 have hearing loss according to the World Health Organisation
People with hearing difficulties experienced heightened self-reported depression, loneliness, and memory problems during the Covid-19 lockdown, according to an online survey of the over 70s.
The study, published in the International Journal of Audiology, was carried out by experts at the University of Sheffield, The University of Manchester andLancaster University.